Journal of Pediatric Neurology 2024; 22(02): 108-113
DOI: 10.1055/s-0044-1786777
Review Article

At the Origin of Brain Malformations: Embryology of the Central and Peripheral Nervous System

Paola Cavallaro*
1   Pediatrics Postgraduate Residency Program, University of Messina, Messina, Italy
,
Michela Leotta*
1   Pediatrics Postgraduate Residency Program, University of Messina, Messina, Italy
,
Daria La Cognata*
2   Pediatrics Postgraduate Residency Program, University of Catania, Catania, Italy
,
Federica Dierna
2   Pediatrics Postgraduate Residency Program, University of Catania, Catania, Italy
,
Valeria Fichera
2   Pediatrics Postgraduate Residency Program, University of Catania, Catania, Italy
,
Michele Vecchio
3   Rehabilitation Unit, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
,
Agata Polizzi
4   Chair of Pediatrics, Department of Educational Sciences, University of Catania, Catania, Italy
,
Andrea D. Praticò
5   Chair of Pediatrics, Department of Medicine and Surgery, Kore University, Enna, Italy
,
Michela Spatuzza
6   Institute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), Unit of Catania, Catania, Italy
,
Paola Castrogiovanni
7   Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
,
Giuseppe Musumeci
7   Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
,
Michelino Di Rosa
7   Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
,
Rossella Imbesi
6   Institute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), Unit of Catania, Catania, Italy
7   Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
› Author Affiliations
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Abstract

Development of the central nervous system is a time-ordered and multistepped process that begins in the third week of development and continues after birth. Understanding of its normal embryologic development is fundamental to understand how specific malformations develop. This article provides a summary of human brain development and serves as a base to introduce the various malformations presented in this issue.

* These authors have equally contributed to this article.




Publication History

Received: 11 December 2023

Accepted: 04 April 2024

Article published online:
13 May 2024

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